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What to Do for Severe Hypoglycemia: A Step-by-Step Emergency Guide
18 Sep 2025 By Dana M. Harris, M.D.

What to Do for Severe Hypoglycemia: A Step-by-Step Emergency Guide

Severe hypoglycemia, or low blood sugar, is a critical condition that requires immediate intervention. It occurs when blood glucose levels drop to dangerously low levels, typically below 70 mg/dL (3.9 mmol/L), and the person is unable to treat themselves due to confusion, disorientation, or loss of consciousness. This guide provides a detailed, step-by-step approach to managing a severe hypoglycemic episode to ensure the safety and well-being of the affected individual. Best Blood Sugar Support Supplements An Evidence Based Look

Understanding the symptoms of severe hypoglycemia and acting swiftly can prevent serious complications like seizures, coma, and even death. This guide is designed to equip you with the knowledge and confidence to respond effectively in such an emergency.

Why Immediate Action Is Crucial

Hypoglycemia can quickly escalate, leading to impaired brain function and physical incapacitation. Glucose is the primary energy source for the brain, and a lack of it can cause rapid deterioration. Prompt intervention is vital to restore blood sugar levels and prevent irreversible damage. The key is recognizing the signs, having a plan, and executing it efficiently.

| Stage of Hypoglycemia | Blood Sugar Level (mg/dL) | Common Symptoms | Action Required | | :------------------------ | :--------------------------- | :---------------------------------------------------- | :---------------------------------------------------- | | Mild | 70-90 | Shakiness, sweating, hunger, irritability | Consume fast-acting carbohydrates | | Moderate | 50-70 | Confusion, difficulty concentrating, blurred vision | Consume fast-acting carbohydrates; monitor symptoms | | Severe | Below 50 | Loss of consciousness, seizures, inability to respond | Administer glucagon; call emergency services |


Step 1: Recognize the Signs and Symptoms of Severe Hypoglycemia

Being able to quickly identify the symptoms of severe hypoglycemia is the first critical step. The symptoms can vary from person to person, but common indicators include:

  • Loss of consciousness: The person is unresponsive or unable to wake up.
  • Seizures: Involuntary muscle contractions or convulsions.
  • Confusion or disorientation: Marked difficulty in thinking clearly or knowing where they are.
  • Inability to swallow: Rendering oral treatments impossible.
  • Unusual behavior: Irrational or aggressive actions that are out of character.

It's crucial to differentiate these symptoms from other medical conditions. However, when in doubt, treat for hypoglycemia, as delaying treatment can have severe consequences. For individuals with diabetes, family members or caregivers should be educated on these symptoms, as early recognition significantly improves outcomes.

Case Example

John, a 55-year-old with type 1 diabetes, was found unconscious by his wife. She recognized the signs of hypoglycemia – his unresponsiveness and clammy skin. Recalling her training, she immediately prepared a glucagon injection.


Step 2: Administer Glucagon (If Available)

Glucagon is a hormone that raises blood sugar levels by prompting the liver to release stored glucose into the bloodstream. It is a life-saving medication for severe hypoglycemia when the person cannot take oral glucose.

How to Administer Glucagon

  1. Locate the Glucagon Kit: If the person has diabetes, they should have a glucagon emergency kit readily available. It usually contains a vial of powdered glucagon and a syringe filled with sterile water.
  2. Prepare the Injection: Follow the instructions on the glucagon kit:
    • Remove the caps from the vial and syringe.
    • Inject the sterile water into the vial of powdered glucagon.
    • Gently roll the vial to mix the solution. Do not shake vigorously, as this can create bubbles.
    • Withdraw the reconstituted glucagon solution back into the syringe.
  3. Administer the Injection:
    • Choose an injection site – typically the upper arm, thigh, or buttocks.
    • Clean the area with an alcohol swab (if available, but don’t delay if not).
    • Pinch the skin and inject the glucagon intramuscularly (at a 90-degree angle).
    • Administer the entire dose – typically 1 mg for adults and half the dose (0.5 mg) for children. However, always follow the prescribing doctor's instructions.
  4. Note the Time: Document the time of the glucagon injection. This is essential information for emergency responders.

Important Considerations for Glucagon Administration

  • Check Expiration Date: Ensure the glucagon hasn’t expired.
  • Proper Mixing: Properly mixing the glucagon solution is critical for it to be effective.
  • Positioning: Lay the person on their side in the recovery position to prevent choking in case of vomiting.
  • No Improvement: If there is no improvement within 15 minutes, follow medical guidelines (often another dose if available), and wait for emergency services to arrive.

| Age Group | Recommended Glucagon Dose | | :------------ | :----------------------------- | | Adults | 1 mg | | Children | 0.5 mg |

Example Scenario

Mary is administering glucagon to her husband. She carefully follows each step, from mixing the solution to selecting the injection site. She checks the time of the injection to track progress. Take Control How To Regulate Blood Sugar With Diet And Exercise


Step 3: Call for Emergency Medical Assistance (911 or Local Equivalent)

Immediately call emergency services. Even if the person starts to recover after a glucagon injection, professional medical evaluation is necessary. Explain the situation clearly to the dispatcher:

  • State the Emergency: "I am calling because someone is experiencing severe hypoglycemia."
  • Provide the Location: Give the exact address where help is needed.
  • Describe the Situation: Explain that the person is unconscious (or seizing) and that you have administered glucagon.
  • Mention Medical History: If known, mention that the person has diabetes and any other relevant medical conditions.
  • Follow Instructions: Answer any questions the dispatcher may have and follow their instructions carefully.

Remain on the phone until the emergency services arrive and can take over the situation. Emergency responders have advanced tools and medications to stabilize the person's condition and transport them to a hospital for further treatment.

Waiting for Emergency Services

While waiting for help to arrive:

  • Monitor Breathing: Ensure the person is breathing adequately. If not, be prepared to perform rescue breathing or CPR if trained.
  • Keep Warm: Cover the person with a blanket to prevent hypothermia.
  • Note Changes: Observe and note any changes in the person's condition to relay to the emergency responders.
  • Stay Calm: Staying calm helps you communicate effectively with emergency services and provide better care.

Table of Emergency Numbers

| Country | Emergency Number | | :---------- | :------------------- | | USA | 911 | | Canada | 911 | | UK | 999 | | Australia | 000 |


Step 4: What to Do After Glucagon Administration

Following glucagon administration, ongoing monitoring is essential.

Monitoring Recovery

  1. Check for Responsiveness: After about 10-15 minutes, check if the person is regaining consciousness and responding to verbal commands.
  2. Monitor Breathing: Continue to observe their breathing pattern for any irregularities.
  3. Check Blood Sugar (if possible): If a blood glucose meter is available, check the person's blood sugar level to confirm it is rising.
  4. Recovery Position: Once conscious, lay the person on their side to prevent choking if vomiting occurs.

Giving Carbohydrates

Once the person is awake and able to swallow, provide a source of fast-acting carbohydrates to replenish their glucose levels:

  • Glucose Tablets or Gel: The fastest and most reliable option.
  • Fruit Juice: About 4 ounces (120 ml) of orange or apple juice.
  • Regular Soda: Not diet soda, about 4 ounces.
  • Hard Candies: Several pieces of hard candy that can be easily chewed and swallowed.

Preventing a Recurrence

After the immediate threat has passed, it's important to prevent another hypoglycemic episode. Give the person a longer-acting source of carbohydrates, such as:

  • Crackers with Peanut Butter
  • A Sandwich
  • A Small Meal

Analyzing the Cause

Work with the affected individual and their healthcare provider to investigate the possible causes of the severe hypoglycemia. This might involve reviewing their:

  • Medication dosages
  • Meal timing
  • Exercise routine
  • Overall health status

Example Analysis

After experiencing a severe hypoglycemic episode, Sarah worked with her doctor to review her insulin dosage and meal plans. They discovered that her insulin dose was too high relative to her carbohydrate intake, leading to the dangerous drop in blood sugar.


Step 5: Educate and Prepare for Future Episodes

Prevention is always better than cure. Proper education and preparation can significantly reduce the risk of severe hypoglycemia. What Is The Difference Between Type 1 And Type 2 Diabetes

Education

  1. Diabetes Education Classes: Enroll in diabetes education programs to learn more about managing blood sugar levels.
  2. Train Family and Friends: Educate family members, friends, and caregivers on how to recognize and treat severe hypoglycemia, including how to administer glucagon.
  3. Carry Medical Identification: Ensure the person wears a medical ID bracelet or necklace indicating they have diabetes.
  4. Regular Doctor Visits: Schedule regular check-ups with the healthcare provider to monitor diabetes management and adjust treatment plans as needed.

Preparation

  1. Glucagon Kit: Always have a glucagon emergency kit readily available at home, work, and when traveling.
  2. Check Expiration Dates: Regularly check the expiration dates of medications and glucagon.
  3. Fast-Acting Carbohydrates: Keep a supply of fast-acting carbohydrates easily accessible.
  4. Emergency Contact List: Have a list of emergency contacts, including the healthcare provider's phone number, readily available.

Sample Checklist

| Item | Status | Location | | :-------------------------- | :--------- | :----------- | | Glucagon Kit | Active | Home, Office | | Fast-Acting Carbs | Stocked | Everywhere | | Medical ID Bracelet | Worn | Always | | Emergency Contact List | Updated | Wallet, Phone|

Conclusion

Severe hypoglycemia is a dangerous condition, but with quick recognition, proper preparation, and decisive action, its serious consequences can be prevented. By following this step-by-step guide, you can be better equipped to respond effectively in an emergency and potentially save a life. It’s imperative to always remember that immediate action is crucial, and ongoing education and prevention strategies are vital for managing diabetes effectively and reducing the risk of hypoglycemic episodes.

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