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What to Do During a Severe Hypoglycemia Event: A Step-by-Step Plan
18 Sep 2025 By Osamah A. Al Ali, M.B., Ch.B.

What to Do During a Severe Hypoglycemia Event: A Step-by-Step Plan

Hypoglycemia, or low blood sugar, is a common concern for individuals with diabetes, particularly those using insulin or certain oral medications. While mild hypoglycemia can often be managed with a quick snack, a severe hypoglycemia event requires immediate and specific intervention to prevent serious complications. This article provides a detailed, step-by-step plan on what to do during a severe hypoglycemia event. Achieving Blood Sugar Balance A Holistic Approach For Better Health

Understanding Severe Hypoglycemia

Before diving into the steps, it's essential to understand what constitutes a severe hypoglycemic event. Severe hypoglycemia typically means that the individual is unable to treat themselves because they are confused, disoriented, unconscious, or having seizures due to low blood sugar levels. It often requires assistance from another person. A blood glucose level below 70 mg/dL (3.9 mmol/L), especially when accompanied by these symptoms, warrants immediate action.

Step-by-Step Plan for Responding to Severe Hypoglycemia

Here’s a practical guide to handling a severe hypoglycemia situation:

Step 1: Recognize the Signs

Prompt recognition is crucial. Common signs of severe hypoglycemia include:

  • Loss of consciousness
  • Seizures
  • Extreme confusion or disorientation
  • Inability to speak or follow commands

Step 2: Do Not Give Food or Drink If Unconscious

If the person is unconscious, do NOT attempt to give them food or drink. Doing so could lead to choking. Focus on safely administering glucagon, as detailed below.

Step 3: Administer Glucagon (If Available and Trained)

Glucagon is a hormone that raises blood sugar levels quickly. It’s available by prescription as an injection or nasal spray and is specifically designed for emergencies like severe hypoglycemia. Simple Ways To Regulate Blood Sugar Naturally For More Energy

  1. Locate the Glucagon Kit: Know where the glucagon kit is stored at home, work, or school.
  2. Check the Expiration Date: Ensure the glucagon hasn’t expired. If it has, use it anyway, but replace it as soon as possible.
  3. Prepare the Injection or Nasal Spray: Follow the specific instructions that come with the glucagon kit.
    • Glucagon Injection: Mix the glucagon powder with the diluent, if required.
    • Glucagon Nasal Spray: This is a ready-to-use device; just remove it from its packaging.
  4. Administer the Glucagon:
    • Injection: Inject the glucagon into the thigh, arm, or buttock. You can inject through clothing if necessary.
    • Nasal Spray: Insert the tip into one nostril and press the plunger to deliver the dose. There is no need to inhale.
  5. Call for Emergency Medical Help Immediately (Dial 911): Even after administering glucagon, it's vital to call for emergency assistance. Explain the situation, including the administration of glucagon, to the emergency responders.

Step 4: Monitor the Person

After administering glucagon, monitor the person closely for any changes. It may take 5-15 minutes for them to regain consciousness. Be patient and reassuring.

Step 5: Prevent Aspiration

If the person vomits after glucagon administration, turn them on their side to prevent choking (aspiration). The Ultimate Guide To Normal Blood Sugar Levels And Your Ideal Range

Step 6: Provide a Fast-Acting Carbohydrate (Once Conscious and Able to Swallow)

Once the person regains consciousness and can swallow safely, give them a fast-acting carbohydrate source to replenish their blood sugar levels and prevent a recurrence of hypoglycemia. Options include:

  • 4-6 ounces of juice
  • Regular (non-diet) soda
  • Glucose tablets or gel (follow package instructions for appropriate dosage)
  • Honey or syrup (about 1 tablespoon)

Step 7: Follow Up with a Longer-Acting Carbohydrate

After the fast-acting carbohydrate, follow up with a longer-acting carbohydrate source such as:

  • Crackers and cheese
  • Peanut butter on toast
  • A small sandwich

This helps to stabilize blood sugar levels and prevent another drop.

Step 8: Seek Medical Evaluation

Even if the person recovers after glucagon administration and carbohydrate intake, a medical evaluation is necessary. The healthcare provider can investigate the cause of the severe hypoglycemic event and adjust the diabetes management plan to prevent future episodes.

Additional Considerations

  • Education is Key: Family members, caregivers, and close friends should be educated about recognizing and treating severe hypoglycemia. Ensure they know how to administer glucagon.
  • Wear Medical Identification: Individuals at risk of severe hypoglycemia should wear medical identification (e.g., a bracelet or necklace) stating they have diabetes and may experience low blood sugar. This can alert emergency responders if the person is unable to communicate.
  • Review Medication and Meal Plans: Regularly review diabetes medications and meal plans with a healthcare provider. Dosage adjustments or dietary changes may be necessary to minimize the risk of hypoglycemic episodes.
  • Check Blood Sugar Regularly: Frequent blood glucose monitoring, especially before meals, after exercise, and before bedtime, can help identify and prevent low blood sugar. Continuous glucose monitors (CGMs) can be especially helpful in detecting trends and alerting users to potential lows.

Risk Factors and Prevention

Several factors can increase the risk of severe hypoglycemia, including:

  • Excessive Insulin Dose: Taking too much insulin or certain oral diabetes medications can lower blood sugar levels excessively.
  • Missed or Delayed Meals: Skipping meals or delaying carbohydrate intake can lead to hypoglycemia, especially if taking insulin.
  • Unplanned Exercise: Physical activity increases insulin sensitivity and can cause blood sugar levels to drop, particularly if not adequately prepared.
  • Alcohol Consumption: Alcohol can impair the liver's ability to release glucose, leading to hypoglycemia.

Preventative measures include:

  • Adhering to Prescribed Medication Regimens: Follow the medication schedule and dosages prescribed by a healthcare provider.
  • Consistent Meal Timing: Eat meals and snacks at regular intervals to maintain stable blood sugar levels.
  • Monitoring Blood Sugar Before, During, and After Exercise: Adjust insulin doses or carbohydrate intake based on exercise intensity and duration.
  • Limiting Alcohol Intake: Consume alcohol in moderation and always with food to prevent hypoglycemia.

Glucagon: A Lifesaving Medication

Glucagon is a vital medication for treating severe hypoglycemia. Understanding how to administer glucagon can be lifesaving. Here's a summary of glucagon products available:

Glucagon Product Administration Method Key Features
Glucagon Emergency Kit (Injection) Intramuscular or subcutaneous injection Requires mixing before injection; traditional form.
Baqsimi (Nasal Spray) Nasal administration Ready-to-use; no mixing required; easy to administer.
Gvoke HypoPen and Gvoke PFS (Pre-filled Syringe) Subcutaneous injection (auto-injector or pre-filled syringe) Ready-to-use; auto-injector option simplifies administration.

Always discuss the best option for your individual needs with your healthcare provider.

Conclusion

Being prepared and knowing how to respond during a severe hypoglycemia event can be life-saving. By following this step-by-step plan, ensuring glucagon is readily available, educating family and friends, and consistently managing diabetes, individuals can minimize the risks associated with severe hypoglycemia. Remember, always consult with a healthcare provider to develop a personalized diabetes management plan that addresses your specific needs and risk factors. Regular monitoring and proactive management are key to maintaining stable blood sugar levels and preventing complications.

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