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What to Do During a Severe Hypoglycemia Episode: A Safety Guide
18 Sep 2025 By Keir MacKay, M.B., B.Ch., B.A.O.

What to Do During a Severe Hypoglycemia Episode: A Safety Guide

Severe hypoglycemia, or low blood sugar, is a critical and potentially life-threatening condition that can occur in individuals with diabetes, particularly those who use insulin or certain oral medications. Understanding how to recognize and manage a severe hypoglycemic episode is vital for both the individual with diabetes and their caregivers. This guide provides essential steps and information to help you navigate such emergencies, ensuring safety and swift action.

Understanding Severe Hypoglycemia

Hypoglycemia occurs when the blood glucose level drops too low, typically below 70 mg/dL (3.9 mmol/L). Severe hypoglycemia is defined as a hypoglycemic episode requiring assistance from another person to administer treatment because the individual is unable to do so themselves due to confusion, disorientation, or loss of consciousness.

| Blood Glucose Level | Condition | Symptoms | |----------------------|-----------------------|-------------------------------------------------------------| | >70 mg/dL (3.9 mmol/L) | Normal | None | | 55-70 mg/dL (3.0-3.9 mmol/L)| Mild Hypoglycemia | Shakiness, sweating, anxiety, hunger | | <55 mg/dL (3.0 mmol/L) | Moderate Hypoglycemia| Confusion, difficulty concentrating, blurred vision, weakness| | Severe Hypoglycemia | Severe Hypoglycemia | Unconsciousness, seizures, inability to swallow |

Recognizing the Signs and Symptoms

The first step in managing severe hypoglycemia is recognizing the signs and symptoms. While mild to moderate hypoglycemia may present with symptoms like shakiness, sweating, and confusion, severe hypoglycemia often involves more pronounced symptoms: A Practical Guide To Managing Type 2 Diabetes Day To Day

  • Loss of consciousness: The individual may faint or become unresponsive.
  • Seizures: Uncontrolled muscle contractions can occur.
  • Inability to swallow: This makes oral treatments dangerous.
  • Marked confusion or disorientation: The person may be unable to follow simple instructions.
  • Slurred speech: Difficulty speaking clearly can mimic intoxication.

Prompt recognition of these signs is crucial for initiating timely intervention and preventing serious complications.


Step-by-Step Guide: Responding to a Severe Hypoglycemic Episode

When faced with a severe hypoglycemic episode, immediate and appropriate action is necessary. Here’s a step-by-step guide to help you respond effectively:

1. Assess the Situation and Ensure Safety

  • Check for responsiveness: Try to wake the person by gently shaking them and speaking loudly.
  • Ensure safety: Move the individual away from any potential hazards, such as sharp objects or busy roads.
  • Call for help: If the person is unconscious or having a seizure, immediately call emergency services (911 in the US) and provide them with the individual's diabetic status.

2. Administer Glucagon (If Available)

Glucagon is a hormone that raises blood sugar levels. It is available as an injectable medication or a nasal spray and is typically prescribed to individuals at risk of severe hypoglycemia. A Quick Way To Lower Blood Sugar After A High Carb Meal

  • Locate the Glucagon Kit: Make sure you know where the glucagon kit is stored.
  • Prepare the Injection/Spray: Follow the instructions on the glucagon kit carefully. For the injectable form, this usually involves mixing a powder with a liquid. For the nasal spray, ensure the nostril is clear.
  • Administer the Glucagon:
    • Injection: Inject the glucagon into the thigh, arm, or buttock. It can be administered through clothing if necessary.
    • Nasal Spray: Insert the nozzle into one nostril and press the plunger to administer the dose.
  • Note the Time: Document the time the glucagon was administered, as this information will be important for medical professionals.

Here's a table summarizing the differences between injectable and nasal glucagon:

| Feature | Injectable Glucagon | Nasal Glucagon | |--------------------|---------------------------------------------------------|------------------------------------------------------------| | Administration | Requires mixing and injection | Ready-to-use nasal spray | | Ease of Use | Can be more challenging, especially for untrained individuals | Easier to administer, even by untrained individuals | | Effectiveness | Highly effective, reliable results | Effective, but absorption can be affected by nasal congestion | | Storage | Requires refrigeration | Room temperature | | Common Side Effects | Nausea, vomiting | Nasal irritation, runny nose | The Ultimate Guide To Regulating Postprandial Blood Sugar After Meal Spikes

3. If Glucagon Is Not Available or You're Unsure How to Use It

  • Call for Emergency Assistance: Do not hesitate to call emergency services (911) if you cannot administer glucagon or if you are unsure how to do so. Paramedics can provide immediate medical attention.
  • Do Not Attempt to Give Food or Drink: If the person is unconscious or unable to swallow, do not try to force food or liquid into their mouth. This can cause choking.

4. Monitor the Individual

  • Stay with the Person: Do not leave the individual alone until they regain consciousness and are able to eat or drink.
  • Check Blood Sugar (If Possible): If you have a glucose meter, check the blood sugar level to confirm that it is rising.
  • Watch for Improvement: Glucagon typically raises blood sugar levels within 10-15 minutes.

5. Once the Person Regains Consciousness

  • Give a Fast-Acting Carbohydrate: Once the person is awake and able to swallow, give them a source of fast-acting carbohydrates, such as juice, glucose tablets, or regular soda (not diet).
  • Follow with a Long-Acting Carbohydrate: After the fast-acting carbohydrate, provide a longer-acting carbohydrate, such as crackers, bread, or a piece of fruit, to prevent a recurrence of hypoglycemia.
  • Monitor Blood Sugar: Check blood sugar levels again after 15-20 minutes to ensure they are rising and stable.

6. Seek Medical Evaluation

  • Contact a Healthcare Provider: After a severe hypoglycemic episode, it is crucial to contact the individual’s healthcare provider to discuss the event and adjust their diabetes management plan, if necessary.
  • Inform Emergency Services: If emergency services were called, ensure they have all the relevant information about the episode and the individual's medical history.

Preventing Future Episodes of Severe Hypoglycemia

Prevention is key to reducing the risk of severe hypoglycemic episodes. Here are some strategies to help:

1. Regular Blood Sugar Monitoring

  • Consistent Checks: Regularly check blood sugar levels, especially before meals, before bedtime, and before and after exercise.
  • Continuous Glucose Monitoring (CGM): Consider using a CGM system, which continuously tracks blood sugar levels and can alert you to potential lows. Research indicates that CGM use can significantly reduce the risk of severe hypoglycemia.

2. Medication Management

  • Adherence: Take diabetes medications as prescribed and on schedule.
  • Coordination: Coordinate insulin doses with meal timing and carbohydrate intake.
  • Regular Review: Periodically review your medication regimen with your healthcare provider to ensure it is appropriate for your current lifestyle and health status.

3. Diet and Exercise Considerations

  • Balanced Meals: Eat balanced meals at regular intervals to maintain stable blood sugar levels.
  • Carbohydrate Awareness: Understand how different foods affect blood sugar levels and adjust insulin doses accordingly.
  • Exercise Planning: Monitor blood sugar levels before, during, and after exercise, and adjust insulin doses or carbohydrate intake as needed.
    • Example: If you plan a rigorous exercise, consume 15-30 grams of carbohydrate before starting to minimize the risk of hypoglycemia.

4. Educate Caregivers and Family Members

  • Training: Teach family members, friends, and caregivers how to recognize the signs of hypoglycemia and how to administer glucagon.
  • Emergency Plan: Develop a written emergency plan that includes contact information for healthcare providers and instructions for managing severe hypoglycemia.

5. Wear a Medical Alert

  • Identification: Wear a medical alert bracelet or necklace that indicates you have diabetes. This will alert first responders to your condition in case of an emergency.

Practical Tips and Considerations

Here are some additional practical tips and considerations for managing severe hypoglycemia:

Glucagon Administration Tips

  • Practice: If possible, practice administering glucagon with a training kit (available from some manufacturers) to become familiar with the process.
  • Expiration Date: Regularly check the expiration date of your glucagon kit and replace it as needed.
  • Storage: Store glucagon in a cool, dry place, as recommended by the manufacturer.

Communication with Healthcare Providers

  • Detailed Logs: Keep a detailed log of hypoglycemic episodes, including the date, time, symptoms, blood sugar level, and treatment administered.
  • Regular Appointments: Attend regular appointments with your endocrinologist or diabetes educator to discuss your diabetes management plan and address any concerns.

Navigating Specific Situations

  • Travel: When traveling, carry extra supplies of glucagon, glucose tablets, and other diabetes essentials. Keep these items with you, rather than in checked baggage.
  • Driving: Check blood sugar levels before driving and every few hours during long trips. Keep a supply of fast-acting carbohydrates in your vehicle.
  • Alcohol Consumption: Be aware that alcohol can increase the risk of hypoglycemia, especially when combined with insulin or oral diabetes medications. Consume alcohol in moderation and always with food.

The Role of Technology

  • Insulin Pumps: Consider using an insulin pump, which can deliver precise doses of insulin and reduce the risk of hypoglycemia.
  • Artificial Pancreas Systems: Explore the option of using an artificial pancreas system (also known as closed-loop systems), which automatically adjusts insulin delivery based on real-time glucose levels.

| Technology | Benefits | Considerations | |---------------------------------|------------------------------------------------------------------------------|------------------------------------------------------------------------------------| | Continuous Glucose Monitoring (CGM) | Real-time glucose readings, alerts for highs and lows | Requires regular calibration, potential for false alarms | | Insulin Pump | Precise insulin delivery, flexibility with meal timing and exercise | Requires training and commitment, risk of pump malfunction | | Artificial Pancreas Systems | Automated glucose control, reduced burden of diabetes management | Requires ongoing monitoring and adjustments, not suitable for everyone |

By following this comprehensive guide, individuals with diabetes and their caregivers can be better prepared to recognize, respond to, and prevent severe hypoglycemic episodes, promoting safety and improving overall quality of life. Remember that timely action and proactive prevention are key to managing this potentially life-threatening condition. Always consult with a healthcare provider for personalized advice and treatment plans.

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