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Severe Hypoglycemia: Emergency Steps for Persons with Diabetes
17 Sep 2025 By Olga M. Petrucelli, M.D.

Severe Hypoglycemia: Emergency Steps for Persons with Diabetes

Severe hypoglycemia, or critically low blood sugar, is a dangerous condition that can occur in people with diabetes. Understanding how to recognize it, and taking swift and effective action, is crucial to prevent serious complications. This article will guide you through the emergency steps to take when someone with diabetes experiences a severe hypoglycemic episode.

What is Severe Hypoglycemia?

Hypoglycemia occurs when the blood glucose level drops too low, usually below 70 mg/dL (3.9 mmol/L). Severe hypoglycemia is defined as hypoglycemia that requires assistance from another person because the individual is unable to treat themselves. This can manifest as confusion, seizures, loss of consciousness, or coma.

For individuals with diabetes, managing blood sugar levels is a constant balancing act involving: - Medication: Insulin or oral diabetes medications can sometimes cause blood sugar to drop too low. - Diet: Skipping meals, not eating enough carbohydrates, or changes in dietary habits can affect glucose levels. - Exercise: Physical activity increases insulin sensitivity and glucose uptake by muscles, which can lower blood sugar.

| Factor | How it can lead to Hypoglycemia | |-------------------|---------------------------------| | Insulin overdose | Too much insulin lowers glucose too rapidly | | Skipped meals | No glucose intake to balance insulin | | Strenuous exercise | Increases glucose uptake by muscles |


Recognizing the Signs and Symptoms

Being able to recognize the signs and symptoms of severe hypoglycemia is essential. It can allow for timely intervention before the situation becomes a full-blown emergency. Symptoms can vary from person to person, but common indicators include:

Early Warning Signs:

  • Shakiness or trembling
  • Sweating
  • Rapid heartbeat
  • Hunger
  • Lightheadedness or dizziness
  • Blurred vision
  • Headache
  • Confusion or difficulty concentrating
  • Irritability or anxiety

Symptoms of Severe Hypoglycemia:

  • Loss of coordination
  • Difficulty speaking
  • Seizures
  • Unconsciousness or coma

It’s crucial to teach family members, friends, and caregivers to recognize these signs, so they can act quickly if the person with diabetes is unable to help themselves.


Emergency Treatment: Step-by-Step Guide

When someone is experiencing severe hypoglycemia, quick and appropriate action is vital. Here are the step-by-step instructions:

1. Assess the Situation and Call for Help

  • Determine responsiveness: Check if the person is conscious and able to follow commands.
  • Call emergency services (911 in the US, or your local emergency number): Immediate medical assistance might be necessary. Let them know the person is experiencing severe hypoglycemia and has diabetes.

2. Administer Glucagon

Glucagon is a hormone that raises blood sugar levels. It is typically prescribed to people with diabetes who are at risk of severe hypoglycemia, and should be kept on hand for emergencies.

  • Locate the Glucagon Kit: Ensure you know where it is stored.
  • Prepare the Injection: Follow the instructions on the kit. Typically, you will need to mix the powder and liquid in the vial.
  • Administer the Injection:
  • Adults and Children over 25 kg (55 lbs): Inject 1 mg of glucagon.
  • Children under 25 kg (55 lbs): Inject 0.5 mg of glucagon (or follow the dosing instructions in the kit, as they may vary by product.)
  • Injection Site: Glucagon can be injected into the upper arm, thigh, or buttock.

Note: Even if the person regains consciousness shortly after the glucagon injection, it is essential to follow through with emergency medical services, as the effect of glucagon is temporary. Your A1C Blood Sugar Chart Understanding Your Target Range

3. If Glucagon Is Unavailable and the Person Is Conscious and Able to Swallow

If glucagon is unavailable, or if you are waiting for it to arrive and the person is conscious and able to swallow, give them a fast-acting source of glucose. Options include:

  • Glucose tablets: Typically, 3-4 glucose tablets (follow the package directions for dosage).
  • Glucose gel: Apply inside the cheek.
  • Fruit juice: About 4 ounces (120 ml).
  • Regular (non-diet) soda: About 4 ounces (120 ml).
  • Hard candies: About 3-4 pieces (avoid chocolate, as the fat content slows glucose absorption).
  • Honey or syrup: About 1 tablespoon.

Wait about 15 minutes and recheck blood glucose if possible. If blood glucose is still low (below 70 mg/dL), repeat the treatment. The A1C Test Explained What It Is And Why It S Crucial For Diabetes Care

4. Position the Person Safely

If the person is unconscious or having a seizure: - Do not give anything by mouth, as this could cause choking. - Turn the person on their side (recovery position) to prevent aspiration if they vomit. - Protect their head from injury if they are having a seizure. - Stay with the person until emergency medical services arrive.

5. Inform Emergency Responders

When the emergency responders arrive, provide them with the following information: - The person’s diabetes status. - Whether glucagon was administered and when. - The person’s current symptoms and any other relevant medical history. - List of medications being taken by the patient

| Action | Description | Rationale | |------------------------------|-------------------------------------------------------------------------------------|-----------------------------------------------------------------------------------------| | Call emergency services | Dial 911 (or local emergency number) immediately. | Ensures rapid medical intervention, particularly if unconscious or unresponsive. | | Administer Glucagon | Inject glucagon according to the kit's instructions. | Raises blood glucose levels quickly to counteract hypoglycemia. | | Glucose source (if conscious) | Provide glucose tablets, juice, soda, or honey. | Provides a quick source of glucose to raise blood sugar levels. | | Safe Positioning | Turn the unconscious person on their side to prevent aspiration. | Prevents choking if vomiting occurs due to low blood sugar. |


Prevention and Education

Preventing severe hypoglycemia is key to maintaining the health and well-being of people with diabetes. Education plays a critical role in prevention. Here are some strategies:

1. Regular Blood Glucose Monitoring

  • Check blood glucose levels: Regularly, especially before meals, after exercise, and at bedtime.
  • Continuous Glucose Monitoring (CGM): Consider a CGM system for continuous monitoring and alerts for low blood sugar.

2. Adjusting Medication and Insulin Doses

  • Work with a healthcare provider: Regularly review and adjust medication and insulin doses based on blood glucose readings, diet, and activity levels.
  • Timing of Insulin: Pay attention to the timing of insulin injections in relation to meals.

3. Meal Planning and Timing

  • Regular meal schedule: Avoid skipping meals and maintain a consistent eating schedule.
  • Carbohydrate intake: Balance carbohydrate intake with medication and activity levels.

4. Exercise Precautions

  • Monitor blood glucose before, during, and after exercise: To understand how exercise affects glucose levels.
  • Carry a fast-acting source of glucose: For quick treatment if blood sugar drops.
  • Adjust insulin doses: As needed, for planned exercise.

5. Educating Family and Friends

  • Teach them to recognize the symptoms: Of hypoglycemia and how to administer glucagon.
  • Keep glucagon easily accessible: And ensure everyone knows where it is located.
  • Emergency contact information: Keep a list of emergency contacts readily available.

6. Wear a Medical Alert

  • Medical ID: Wear a medical ID bracelet or necklace indicating you have diabetes.
  • Inform about conditions: This can help emergency responders provide appropriate care if you are unable to communicate.

| Prevention Strategy | Description | Benefit | |---------------------------|----------------------------------------------------------------------------------|--------------------------------------------------------------------------------------------------| | Regular BG Monitoring | Check blood glucose frequently, use CGM if possible. | Early detection of low blood sugar levels. | | Med Adjustment | Work with healthcare provider to adjust medications based on BG readings. | Prevents drastic drops in blood sugar. | | Consistent Meal Schedule | Avoid skipping meals; eat at regular times. | Maintains stable blood glucose levels. | | Exercise Precautions | Monitor blood glucose before, during, and after exercise; carry glucose. | Prevents exercise-induced hypoglycemia. | | Educate Others | Teach family and friends about hypoglycemia and glucagon administration. | Ensures prompt response during emergencies. | | Medical Alert | Wear a medical ID indicating diabetes. | Alerts first responders about the condition. |


The Role of Technology

Modern technology offers several tools to aid in the prevention and management of severe hypoglycemia:

Continuous Glucose Monitoring (CGM)

  • Real-time tracking: CGM systems provide continuous, real-time blood glucose readings, alerting users and caregivers to impending lows.
  • Trend analysis: These devices also show trends, predicting whether blood sugar is rising or falling rapidly, allowing for proactive adjustments.
  • Alerts: CGMs can be programmed to send alerts when blood glucose drops below a certain threshold, prompting timely intervention.

Insulin Pumps with Automated Insulin Suspension

  • Suspend before low: Some insulin pumps can automatically suspend insulin delivery when blood glucose levels are predicted to drop too low.
  • Closed-loop systems: Advanced systems can adjust insulin delivery based on CGM readings, mimicking the function of a healthy pancreas.

Smartphone Apps

  • Glucose tracking: Apps allow users to log blood glucose readings, track trends, and receive reminders to check their blood sugar.
  • Meal and exercise tracking: Users can also log meals and physical activity, helping them understand how these factors affect their blood glucose levels.
  • Data sharing: Some apps allow users to share their data with healthcare providers for remote monitoring and support.

Artificial Pancreas Systems

  • Hybrid closed-loop systems: These systems combine CGM technology with insulin pumps and sophisticated algorithms to automatically adjust insulin delivery based on real-time blood glucose levels.
  • Improved glycemic control: Studies have shown that artificial pancreas systems can improve glycemic control and reduce the risk of hypoglycemia in people with diabetes.

| Technology | Description | Benefit | |------------------------|----------------------------------------------------------------------------------------------|-------------------------------------------------------------------------------------------------------| | Continuous Glucose Monitoring | Provides continuous blood glucose readings and alerts for impending lows. | Allows for proactive management of blood glucose and reduces the risk of hypoglycemia. | | Automated Insulin Suspension | Suspends insulin delivery when blood glucose is predicted to drop too low. | Prevents or mitigates hypoglycemic episodes by reducing insulin delivery when glucose is trending downward. | | Smartphone Apps | Tracks blood glucose, meals, and exercise; allows data sharing with healthcare providers. | Facilitates comprehensive diabetes management and enhances communication with healthcare professionals. | | Artificial Pancreas Systems | Automatically adjusts insulin delivery based on real-time blood glucose levels. | Improves glycemic control and reduces the risk of hypoglycemia. | The A1C Test Explained What Your Results Mean For Your Health


Conclusion

Severe hypoglycemia is a serious and potentially life-threatening condition for individuals with diabetes. Recognizing the signs, knowing how to administer glucagon or other quick glucose sources, and educating those around you are critical steps in managing such emergencies. In addition to immediate treatment, focusing on prevention through regular monitoring, proper medication management, and lifestyle adjustments can significantly reduce the risk of severe hypoglycemic events. With advancements in technology, such as CGMs and automated insulin delivery systems, managing diabetes and preventing severe hypoglycemia has become more manageable, but vigilance and preparation remain key to ensuring the safety and well-being of individuals living with this condition.

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