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Hello friends, There are many medications now that are FDA approved for weight loss -- what are they and how well do they work? Let's go through the data! References: Bays H, McCarthy W, Burridge K, Tondt J, Karjoo S, Christensen S, Ng J, Golden A, Davisson L, Richardson L. Obesity Algorithm, presented by the Obesity Medicine Association 2021. WT Garvey et al. Step 5 Study Group. Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial. Nat Med. 2022 Oct;28(10):2083-2091. PMID: 36216945 BT Grover et al. Defining Weight Loss After Bariatric Surgery: a Call for Standardization. Obes Surg. 2019 Nov;29(11):3493-3499. PMID: 31256357 AM Jastreboff et al. SURMOUNT 1 Trial. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med 2022; 387:205-216. PMID: 35658024 X Pi-Sunyer et al. A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. N Engl J Med. 2015. Jul 2;373(1):11-22. PMID: 26132939 DM Rubino et al. Step 8 Investigators. Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial. JAMA. 2022 Jan 11;327(2):138-150. PMID: 35015037 JPH Wilding et al. STEP 1 Trial. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021 Mar 18;384(11):989-1002. PMID: 33567185