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Hyperglycemia (High Blood Sugar): Warning Signs You Can't Ignore
17 Sep 2025 By Tina Ardon, M.D., FAAFP

Hyperglycemia (High Blood Sugar): Warning Signs You Can't Ignore

Hyperglycemia, commonly known as high blood sugar, is a condition in which there's an excessive amount of glucose in the bloodstream. This usually occurs because the body doesn't have enough insulin or can't use insulin properly. Insulin, a hormone produced by the pancreas, helps glucose from food get into cells to be used for energy. When glucose can't enter the cells, it builds up in the blood, leading to hyperglycemia.

It is a hallmark of diabetes mellitus, but it can also occur in people without diabetes under certain circumstances such as during acute illness or stress. Recognizing the warning signs of hyperglycemia and taking appropriate action is crucial for preventing severe health complications.

Why is managing blood sugar levels important? Chronically high blood sugar can lead to a range of severe health issues, including:

  • Heart disease: High glucose levels damage blood vessels, increasing the risk of atherosclerosis (plaque buildup).
  • Nerve damage (Neuropathy): Excess glucose can injure nerve fibers throughout your body.
  • Kidney damage (Nephropathy): The kidneys have to work harder to filter the blood, eventually leading to kidney failure.
  • Eye damage (Retinopathy): High blood sugar can damage the blood vessels in the retina, potentially causing blindness.
  • Foot problems: Nerve damage and poor circulation increase the risk of foot ulcers and infections, possibly leading to amputation.

Understanding the Causes of Hyperglycemia

To effectively manage hyperglycemia, it’s essential to understand its root causes. These can vary based on individual circumstances and underlying health conditions. Here's a detailed breakdown of factors that commonly contribute to elevated blood sugar levels:

  1. Insufficient Insulin Production:

    • Type 1 Diabetes: An autoimmune condition where the body attacks and destroys the insulin-producing cells in the pancreas. Without insulin, glucose can't enter cells, causing it to accumulate in the bloodstream.
    • Advanced Type 2 Diabetes: Over time, the pancreas in individuals with type 2 diabetes may lose its ability to produce sufficient insulin.
    • Insulin Resistance:

    • Type 2 Diabetes: Cells become resistant to the effects of insulin, requiring the pancreas to produce more insulin to achieve the same effect. Eventually, the pancreas may not be able to keep up with the demand.

    • Obesity: Excess weight, especially abdominal fat, is strongly associated with insulin resistance. Fat cells release hormones and other substances that interfere with insulin signaling.
    • Sedentary Lifestyle: Lack of physical activity reduces the body's sensitivity to insulin, making it harder for glucose to enter cells.
    • Dietary Factors:

    • High Carbohydrate Intake: Consuming large amounts of carbohydrates, especially refined carbs and sugary foods, can quickly raise blood glucose levels.

    • Portion Sizes: Overeating, even with healthy foods, can lead to an excess of glucose that the body struggles to manage.
    • Medications:

    • Corticosteroids: These anti-inflammatory drugs can increase blood sugar levels by making the liver release more glucose and reducing insulin sensitivity.

    • Certain Antipsychotics: Some antipsychotic medications can affect glucose metabolism and increase the risk of hyperglycemia.
    • Diuretics: Thiazide diuretics, commonly used to treat high blood pressure, can sometimes raise blood sugar levels.
    • Illness and Stress:

    • Physical Stress: When the body is under stress from illness, injury, or surgery, it releases hormones like cortisol and adrenaline, which can increase blood sugar levels.

    • Infections: Infections can trigger the release of stress hormones and inflammatory substances that interfere with insulin action.
    • Other Medical Conditions:

    • Polycystic Ovary Syndrome (PCOS): This hormonal disorder is often associated with insulin resistance and an increased risk of type 2 diabetes.

    • Gestational Diabetes: During pregnancy, some women develop insulin resistance, leading to gestational diabetes, which typically resolves after childbirth.

Common Warning Signs of Hyperglycemia

Being able to identify the symptoms of hyperglycemia is vital for early detection and intervention. Here are some of the most common warning signs of high blood sugar that you should never ignore:

  1. Frequent Urination (Polyuria): When blood sugar is high, the kidneys try to flush out the excess glucose through urine. This leads to more frequent trips to the bathroom, especially at night. Lifestyle Changes For Better Control Of Blood Glucose Levels

  2. Excessive Thirst (Polydipsia): Because the body loses fluids through frequent urination, you'll feel extremely thirsty. No matter how much you drink, it might not feel like enough.

  3. Unexplained Fatigue: High blood sugar can prevent your cells from getting the energy they need, leading to constant tiredness and weakness. This fatigue isn’t relieved by rest.

  4. Blurred Vision: High glucose levels can cause fluid to be pulled from the lenses of your eyes, leading to blurry vision. While this can sometimes be temporary, recurring episodes can damage the eyes over time.

  5. Slow-Healing Cuts and Sores: Elevated blood sugar can impair blood circulation and nerve function, making it difficult for wounds to heal properly. Even minor cuts can take weeks or months to close.

  6. Dry, Itchy Skin: Hyperglycemia can cause dehydration, which leads to dry, itchy skin. Poor circulation can also contribute to skin problems.

  7. Increased Hunger (Polyphagia): Even though your blood sugar is high, your cells aren’t getting enough glucose, which triggers constant hunger. You might eat more but still feel hungry.

  8. Numbness or Tingling in Hands and Feet (Neuropathy): High blood sugar can damage nerves, leading to tingling, numbness, burning, or pain in the extremities. This condition, known as peripheral neuropathy, can worsen over time.

  9. Recurring Infections: High blood sugar weakens the immune system, making you more susceptible to infections, especially urinary tract infections (UTIs), yeast infections, and skin infections.

  10. Unexplained Weight Loss: In some cases, especially with undiagnosed or poorly managed diabetes, you might experience unexplained weight loss despite eating normally or even more than usual. This is because your body can’t effectively use glucose for energy and starts breaking down muscle and fat.

Real-Life Example: Recognizing Early Symptoms

Consider Sarah, a 45-year-old office worker who noticed she was constantly thirsty and had to urinate every hour, even at night. She initially dismissed it as simply needing to drink more water, but the symptoms persisted. She also felt incredibly tired, despite getting adequate sleep. After a few weeks, she noticed her vision was occasionally blurry, and a small cut on her finger took much longer to heal than usual. Recognizing these as warning signs of hyperglycemia, Sarah visited her doctor, who diagnosed her with type 2 diabetes. Because she caught it early, Sarah was able to manage her blood sugar with diet, exercise, and medication, preventing more serious complications.

What to Do If You Suspect Hyperglycemia

If you experience any of the symptoms of hyperglycemia, it's crucial to take immediate action:

  1. Check Your Blood Sugar: If you have diabetes, use your blood glucose meter to check your blood sugar level. If it's higher than your target range, follow your healthcare provider’s instructions for bringing it down.
  2. Hydrate: Drink plenty of water to help flush out excess glucose and prevent dehydration. Avoid sugary drinks like soda and juice.
  3. Adjust Your Diet: If you know you’ve recently consumed a high-carbohydrate meal, adjust your diet accordingly. Choose low-carb, high-fiber foods that release glucose slowly.
  4. Exercise: Physical activity can help lower blood sugar by making your cells more sensitive to insulin. A brisk walk or light exercise can make a significant difference, but avoid strenuous activity if your blood sugar is very high, as this can sometimes have the opposite effect.
  5. Contact Your Healthcare Provider: If you don't have diabetes but suspect you might have hyperglycemia, see a doctor as soon as possible for a diagnosis and treatment plan. Also, contact your healthcare provider if you have diabetes and are unable to manage your blood sugar levels with your usual methods.

When to Seek Emergency Medical Attention: In some cases, hyperglycemia can lead to dangerous complications that require immediate medical care. Seek emergency attention if you experience any of the following symptoms:

  • Severe Abdominal Pain: This can be a sign of diabetic ketoacidosis (DKA), a serious condition that occurs when the body produces high levels of ketones (acids) due to insufficient insulin.
  • Nausea and Vomiting: Persistent nausea and vomiting can also indicate DKA, especially if accompanied by high blood sugar levels.
  • Shortness of Breath: Difficulty breathing or rapid, shallow breaths can be a sign of metabolic acidosis, another complication of DKA.
  • Confusion or Difficulty Staying Awake: Altered mental status, confusion, or difficulty staying awake can indicate severe hyperglycemia or DKA and requires immediate medical attention.
  • Fruity-Scented Breath: This is a classic sign of DKA, caused by the buildup of ketones in the body.
  • Loss of Consciousness: If someone with diabetes loses consciousness, it could be due to extremely high or low blood sugar, both of which require emergency treatment.

Example Scenario: Addressing High Blood Sugar at Home

John, who has type 2 diabetes, checks his blood sugar before dinner and finds it’s 250 mg/dL, significantly above his target range of 80-130 mg/dL. Here's what he should do:

  1. Drink Water: John immediately drinks a large glass of water to rehydrate his body.
  2. Review His Recent Meals: He realizes he had a larger serving of pasta at lunch than usual.
  3. Engage in Light Exercise: After dinner, he takes a 30-minute walk around his neighborhood to help lower his blood sugar.
  4. Monitor His Blood Sugar: He checks his blood sugar again before bed. If it’s still high, he’ll consult his diabetes management plan or contact his doctor.

Practical Strategies for Preventing Hyperglycemia

Preventing hyperglycemia involves adopting a combination of lifestyle changes and consistent monitoring. Here are some practical strategies for preventing high blood sugar:

  1. Maintain a Balanced Diet:

    • Focus on Complex Carbohydrates: Choose whole grains, vegetables, and fruits over refined carbs like white bread, pasta, and sugary snacks.
    • Limit Sugary Drinks: Avoid soda, juice, and sweetened beverages, which can quickly raise blood sugar levels.
    • Control Portion Sizes: Be mindful of how much you’re eating, especially carbohydrates. Use smaller plates and measure portions to avoid overeating.
    • Include Fiber-Rich Foods: Fiber helps slow down the absorption of glucose, preventing rapid spikes in blood sugar. Good sources include beans, lentils, oats, and leafy greens.
    • Engage in Regular Physical Activity:

    • Aim for at Least 150 Minutes of Moderate-Intensity Exercise Per Week: This can include brisk walking, cycling, swimming, or dancing.

    • Incorporate Strength Training: Strength training exercises, such as lifting weights or doing bodyweight exercises, can improve insulin sensitivity and help manage blood sugar.
    • Break Up Sedentary Time: If you spend long periods sitting, take frequent breaks to stand up, stretch, or walk around.
    • Monitor Your Blood Sugar Regularly:

    • Check Your Blood Sugar as Directed by Your Healthcare Provider: If you have diabetes, it’s crucial to monitor your blood sugar levels regularly using a blood glucose meter. Severe Hypoglycemia What To Do In A Low Blood Sugar Emergency

    • Keep a Log of Your Blood Sugar Readings: This will help you and your healthcare provider identify patterns and adjust your treatment plan accordingly.
    • Understand Your Target Range: Know your target blood sugar levels and what to do if your readings are consistently outside of that range.
    • Manage Stress:

    • Practice Relaxation Techniques: Incorporate stress-reducing activities into your daily routine, such as meditation, yoga, deep breathing exercises, or spending time in nature.

    • Get Enough Sleep: Aim for 7-8 hours of quality sleep per night to help regulate stress hormones and improve insulin sensitivity.
    • Seek Support: Talk to friends, family, or a therapist about your stress and develop healthy coping strategies.
    • Take Medications as Prescribed:

    • Follow Your Healthcare Provider’s Instructions: If you have diabetes, take your medications as prescribed and don’t skip doses. Mastering Your Metabolism How Glucose Control Can Change Your Life

    • Understand Your Medications: Know how your medications work, their potential side effects, and when to take them.
    • Inform Your Doctor About Other Medications: Let your healthcare provider know about all the medications and supplements you’re taking, as some can affect blood sugar levels.
    • Maintain a Healthy Weight:

    • Aim for a Healthy Body Mass Index (BMI): Work with your healthcare provider or a registered dietitian to develop a plan for achieving and maintaining a healthy weight.

    • Focus on Sustainable Lifestyle Changes: Avoid fad diets and focus on making long-term, sustainable changes to your eating and exercise habits.
    • Stay Hydrated:

    • Drink Plenty of Water Throughout the Day: Dehydration can raise blood sugar levels, so aim to drink at least 8 glasses of water per day.

    • Avoid Sugary Drinks: As mentioned earlier, sugary drinks can quickly raise blood sugar levels and should be avoided.
    • Regular Medical Check-Ups:

    • Schedule Regular Appointments with Your Healthcare Provider: This will allow them to monitor your overall health and make any necessary adjustments to your treatment plan.

    • Get Screened for Diabetes: If you have risk factors for diabetes, such as a family history of the disease, obesity, or a sedentary lifestyle, get screened regularly.

Practical Tip: Setting Realistic Goals

  • Start small and gradually increase the intensity and duration of your physical activity. For example, begin with 10-minute walks and gradually increase to 30-minute brisk walks.
  • Set specific, measurable, achievable, relevant, and time-bound (SMART) goals. For example, "I will walk for 30 minutes, three times a week" is a SMART goal.

The information provided in this article is intended for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

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