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From A1C to CGM: A Complete Glossary of Diabetes and Blood Sugar Terms
17 Sep 2025 By Christopher T. Pullins, M.D.

From A1C to CGM: A Complete Glossary of Diabetes and Blood Sugar Terms

Understanding diabetes and managing blood sugar levels involves a unique vocabulary. This comprehensive glossary is designed to help you navigate the complex world of diabetes-related terms, from common abbreviations to more technical jargon. Whether you’re newly diagnosed, supporting a loved one, or simply seeking to expand your knowledge, this guide will provide clarity and confidence in understanding diabetes. Let's dive into the essential terms, acronyms, and phrases you need to know.

A is for A1C and Autoimmunity: Essential Starting Points

The journey into understanding diabetes starts with key foundational concepts. These terms provide a starting point for grasping the mechanisms and measurements involved in diabetes management.

A1C (Glycated Hemoglobin)

The A1C test, also known as glycated hemoglobin, measures your average blood sugar level over the past 2-3 months. It reflects the percentage of your red blood cells that have glucose attached to them.

  • Why it Matters: A higher A1C indicates higher average blood sugar levels and poorer blood sugar control.
  • Target Range: The general target for people with diabetes is an A1C of less than 7%, but this may vary based on individual factors.
  • Example: An A1C of 7% corresponds to an estimated average glucose level of 154 mg/dL. | A1C (%) | eAG (mg/dL) | eAG (mmol/L) | | ------- | ----------- | ------------ | | 6 | 126 | 7.0 | | 7 | 154 | 8.6 | | 8 | 183 | 10.1 | | 9 | 212 | 11.8 | | 10 | 240 | 13.4 |

Autoimmunity

Autoimmunity is a condition where your immune system mistakenly attacks your body's own cells. In type 1 diabetes, the immune system attacks and destroys the insulin-producing beta cells in the pancreas.

  • Why it Matters: Understanding autoimmunity is crucial in comprehending the underlying cause of type 1 diabetes.
  • Relevance: Autoimmune diseases, like type 1 diabetes, require specialized treatment strategies that address the immune system’s role.

B is for Basal Rate and Blood Glucose: The Core of Daily Management

Next, we tackle terms crucial for daily blood sugar management. Understanding these terms is essential for those living with diabetes to make informed decisions about diet, exercise, and medication.

Basal Rate

The basal rate is the continuous, low-level insulin that your body needs throughout the day and night, even when you are not eating. It's often delivered via an insulin pump to maintain stable blood sugar levels. How To Lower Your A1C Blood Sugar Level Naturally In 3 Months

  • Why it Matters: A properly calibrated basal rate ensures that blood sugar remains in the target range between meals and during sleep.
  • Adjustment: Basal rates may need adjustment based on factors such as activity level, illness, or hormonal changes.
  • Example: A person might have a basal rate of 0.5 units of insulin per hour during the day and 0.3 units per hour overnight.

Blood Glucose (Blood Sugar)

Blood glucose, often referred to as blood sugar, is the concentration of glucose in the blood. It’s measured in milligrams per deciliter (mg/dL) or millimoles per liter (mmol/L).

  • Why it Matters: Monitoring blood glucose levels is fundamental to diabetes management, helping individuals make informed decisions about diet, exercise, and medication.
  • Target Range: The typical target range for blood glucose is 80-130 mg/dL before meals and less than 180 mg/dL two hours after starting a meal.
  • Variations: Blood glucose levels fluctuate throughout the day due to food intake, physical activity, stress, and medication.

C is for Carbohydrates and CGM: Nutrition and Technology

Moving into nutrition and technology, these terms shed light on how dietary choices and modern tools influence blood sugar control.

Carbohydrates

Carbohydrates are one of the three macronutrients in our diet (along with proteins and fats). They are the body's primary source of energy and have a significant impact on blood sugar levels.

  • Why it Matters: Understanding how different types of carbs affect blood sugar is vital for managing diabetes.
  • Types of Carbs:
    • Simple Carbs (Sugars): Found in fruits, table sugar, and processed foods; they are quickly absorbed.
    • Complex Carbs (Starches): Found in whole grains, vegetables, and legumes; they are digested more slowly.
    • Fiber: A type of carbohydrate that the body cannot digest, helping to regulate blood sugar and promote gut health.

CGM (Continuous Glucose Monitor)

A continuous glucose monitor (CGM) is a device that tracks glucose levels in real-time, using a small sensor inserted under the skin.

  • Why it Matters: CGMs provide continuous data, alerting users to trends and fluctuations that fingerstick testing alone cannot capture.
  • Benefits:
    • Real-time glucose readings
    • Alerts for high and low glucose levels
    • Data for identifying patterns and adjusting treatment
  • Examples: Popular CGMs include Dexcom, Abbott FreeStyle Libre, and Medtronic Guardian.

D is for DKA and Dawn Phenomenon: Understanding Complications and Natural Occurrences

Diabetes management also involves understanding potential complications and natural physiological events that affect blood sugar.

DKA (Diabetic Ketoacidosis)

Diabetic Ketoacidosis (DKA) is a serious complication of diabetes that occurs when the body produces high levels of blood acids called ketones. It usually happens when there is not enough insulin in the body.

  • Why it Matters: DKA is a medical emergency requiring immediate treatment to prevent severe consequences.
  • Symptoms: Include excessive thirst, frequent urination, nausea, abdominal pain, weakness, and a fruity odor on the breath.
  • Causes: Often triggered by missed insulin doses, illness, or infection.

Dawn Phenomenon

The dawn phenomenon is a natural rise in blood sugar that occurs in the early morning hours, typically between 3 AM and 8 AM.

  • Why it Matters: Understanding the dawn phenomenon helps in adjusting overnight insulin doses or meal timings to prevent hyperglycemia in the morning.
  • Cause: Believed to be caused by the release of hormones such as cortisol and growth hormone during the night.

E is for Exercise and Endocrine System: The Importance of Activity and Hormonal Regulation

Physical activity and hormonal balance play critical roles in managing blood sugar and overall health.

Exercise

Exercise refers to physical activity that enhances or maintains physical fitness and overall health.

  • Why it Matters: Regular exercise improves insulin sensitivity, helps control blood sugar levels, and reduces the risk of heart disease and other complications of diabetes.
  • Benefits:
    • Lowers blood sugar levels
    • Improves insulin sensitivity
    • Helps maintain a healthy weight
    • Reduces stress
  • Precautions: Monitor blood sugar levels before, during, and after exercise, and adjust insulin or carbohydrate intake as needed.

Endocrine System

The endocrine system is a network of glands that produce and secrete hormones, which regulate various bodily functions, including blood sugar control.

  • Why it Matters: Understanding the endocrine system is crucial for comprehending how hormones like insulin, glucagon, and cortisol affect blood sugar levels.
  • Key Hormones:
    • Insulin: Lowers blood sugar levels.
    • Glucagon: Raises blood sugar levels.
    • Cortisol: Can raise blood sugar levels, especially during stress.

F is for Fasting Plasma Glucose (FPG): Diagnostic Criteria

Diagnostic tests like the Fasting Plasma Glucose are fundamental for identifying and classifying diabetes.

Fasting Plasma Glucose (FPG)

Fasting Plasma Glucose (FPG) is a blood glucose test taken after an overnight fast of at least 8 hours.

  • Why it Matters: FPG is a common diagnostic test for diabetes and prediabetes.
  • Interpretation:
    • Normal: Less than 100 mg/dL
    • Prediabetes: 100-125 mg/dL
    • Diabetes: 126 mg/dL or higher on two separate tests.

G is for Gestational Diabetes and Glucagon: Pregnancy and Emergency Treatments

These terms relate to specific contexts, like pregnancy and emergency situations, where blood sugar management requires tailored strategies.

Gestational Diabetes

Gestational diabetes is a type of diabetes that develops during pregnancy in women who did not have diabetes before.

  • Why it Matters: Managing gestational diabetes is vital for the health of both the mother and the baby.
  • Risks: High blood sugar levels during pregnancy can lead to complications such as large birth weight, preterm birth, and an increased risk of developing type 2 diabetes later in life.
  • Management: Usually involves dietary changes, exercise, and sometimes insulin therapy.

Glucagon

Glucagon is a hormone produced by the pancreas that raises blood sugar levels by stimulating the liver to release stored glucose.

  • Why it Matters: Glucagon is used as an emergency treatment for severe hypoglycemia (low blood sugar) in people with diabetes.
  • Administration: Glucagon is available as an injection or nasal spray and can be administered by a caregiver or trained individual.

H is for Hyperglycemia and Hypoglycemia: Understanding Highs and Lows

Recognizing and managing both high and low blood sugar levels is crucial for maintaining health and preventing complications.

Hyperglycemia (High Blood Sugar)

Hyperglycemia, or high blood sugar, occurs when glucose levels in the blood are too high.

  • Why it Matters: Chronic hyperglycemia can lead to long-term complications such as nerve damage, kidney damage, and heart disease.
  • Symptoms: Include increased thirst, frequent urination, blurred vision, and fatigue.
  • Causes: Often caused by overeating, not taking enough insulin, illness, or stress.

Hypoglycemia (Low Blood Sugar)

Hypoglycemia, or low blood sugar, occurs when glucose levels in the blood are too low.

  • Why it Matters: Severe hypoglycemia can lead to confusion, seizures, loss of consciousness, and even death if left untreated.
  • Symptoms: Include shakiness, sweating, hunger, dizziness, confusion, and irritability.
  • Treatment: Mild hypoglycemia can be treated by consuming fast-acting carbohydrates such as glucose tablets, juice, or hard candies.

I is for Insulin and Insulin Resistance: The Core Concepts of Diabetes

Insulin is a critical hormone in diabetes management, and understanding insulin resistance is key to comprehending type 2 diabetes.

Insulin

Insulin is a hormone produced by the pancreas that helps glucose from food enter cells to be used for energy.

  • Why it Matters: People with type 1 diabetes do not produce insulin, and many people with type 2 diabetes do not produce enough insulin or are resistant to its effects.
  • Types of Insulin:
    • Rapid-acting: Starts working quickly (15 minutes) and lasts for 2-4 hours.
    • Short-acting: Starts working in 30 minutes to 1 hour and lasts for 3-6 hours.
    • Intermediate-acting: Starts working in 2-4 hours and lasts for 12-18 hours.
    • Long-acting: Starts working in several hours and lasts for 24 hours or more.

Insulin Resistance

Insulin resistance is a condition in which cells in the muscles, fat, and liver do not respond well to insulin and cannot easily take up glucose from the blood.

  • Why it Matters: Insulin resistance is a hallmark of type 2 diabetes and can lead to high blood sugar levels.
  • Causes: Often linked to obesity, physical inactivity, genetic factors, and other medical conditions.

K is for Ketones: Understanding the Byproduct of Fat Metabolism

Ketones are a critical marker in diabetes management, particularly in situations where the body isn't using glucose effectively.

Ketones

Ketones are chemicals that the body makes when it doesn't have enough insulin to use glucose for energy and instead breaks down fat.

  • Why it Matters: High levels of ketones can lead to a dangerous condition called ketoacidosis.
  • Monitoring: Important to monitor ketone levels, especially during illness or when blood sugar is high.
  • Methods: Ketones can be measured in the blood or urine.

L is for Lipids: The Importance of Monitoring Fat Levels

Monitoring lipid levels is crucial in diabetes management due to the increased risk of cardiovascular complications.

Lipids

Lipids, or fats, are a group of naturally occurring molecules that include fats, oils, and cholesterol. From A1C To Glucose A Simple Glossary Of Diabetes Blood Sugar Terms

  • Why it Matters: People with diabetes are at higher risk of developing abnormal lipid levels, which can increase the risk of heart disease and stroke.
  • Key Lipids:
    • Total Cholesterol: A measure of all cholesterol in your blood.
    • LDL Cholesterol (Bad Cholesterol): Can build up in the arteries and increase the risk of heart disease.
    • HDL Cholesterol (Good Cholesterol): Helps remove LDL cholesterol from the arteries.
    • Triglycerides: A type of fat in the blood that can increase the risk of heart disease when levels are high.

M is for Meal Planning: A Cornerstone of Diabetes Management

Effective meal planning is essential for managing blood sugar levels and maintaining a healthy lifestyle with diabetes.

Meal Planning

Meal planning involves making conscious choices about what and when you eat to help manage blood sugar levels.

  • Why it Matters: Proper meal planning ensures a balanced intake of nutrients and helps prevent spikes and drops in blood sugar.
  • Key Strategies:
    • Carb Counting: Tracking the amount of carbohydrates consumed at each meal.
    • Portion Control: Eating appropriate serving sizes to manage calorie and carbohydrate intake.
    • Balanced Diet: Including a mix of carbohydrates, proteins, and healthy fats in each meal.

O is for Oral Glucose Tolerance Test (OGTT): Another Diagnostic Tool

The OGTT is another key diagnostic test used to assess how the body processes glucose, especially relevant in gestational diabetes.

Oral Glucose Tolerance Test (OGTT)

The Oral Glucose Tolerance Test (OGTT) is a test used to diagnose diabetes and gestational diabetes. It measures how well the body processes glucose after consuming a sugary drink.

  • Why it Matters: Provides a comprehensive assessment of glucose metabolism over a period of time.
  • Procedure: Involves fasting for at least 8 hours, then drinking a sugary solution. Blood sugar levels are measured at specific intervals (e.g., 1 hour, 2 hours) after drinking the solution.

P is for Prediabetes and Postprandial: Early Detection and Post-Meal Monitoring

These terms highlight the importance of early detection and monitoring blood sugar levels after eating.

Prediabetes

Prediabetes is a condition in which blood sugar levels are higher than normal but not high enough to be diagnosed as diabetes. Decoding The Normal Blood Sugar Range For Every Age

  • Why it Matters: Prediabetes is a warning sign that you are at risk of developing type 2 diabetes.
  • Reversal: Lifestyle changes such as diet and exercise can often prevent or delay the progression to type 2 diabetes.

Postprandial

Postprandial refers to the period after a meal, typically 1-2 hours after eating.

  • Why it Matters: Monitoring postprandial blood sugar levels helps assess how your body responds to the food you eat.
  • Target Range: Postprandial blood sugar levels should generally be less than 180 mg/dL two hours after starting a meal.

R is for Retinopathy: Understanding Diabetes-Related Eye Complications

Recognizing and addressing potential complications like retinopathy is crucial for preserving long-term health.

Retinopathy

Retinopathy, specifically diabetic retinopathy, is damage to the blood vessels in the retina (the light-sensitive tissue at the back of the eye) caused by diabetes.

  • Why it Matters: Diabetic retinopathy is a leading cause of blindness in adults.
  • Prevention: Regular eye exams and good blood sugar control can help prevent or slow the progression of retinopathy.

S is for Sulfonylureas and Self-Monitoring of Blood Glucose (SMBG): Medication and Monitoring

Medication and regular self-monitoring form the backbone of effective diabetes management strategies.

Sulfonylureas

Sulfonylureas are a class of oral medications used to treat type 2 diabetes. They work by stimulating the pancreas to release more insulin.

  • Why it Matters: An option for managing blood sugar levels in people with type 2 diabetes who still have some insulin production.
  • Examples: Include glipizide, glyburide, and glimepiride.

Self-Monitoring of Blood Glucose (SMBG)

Self-Monitoring of Blood Glucose (SMBG) is the process of regularly checking your blood sugar levels using a blood glucose meter.

  • Why it Matters: SMBG helps individuals make informed decisions about their diet, exercise, and medication.
  • Frequency: The frequency of SMBG depends on individual needs and treatment plans, often recommended several times a day for those on insulin.

T is for Type 1 Diabetes and Type 2 Diabetes: The Two Primary Forms of the Condition

Understanding the distinctions between Type 1 and Type 2 diabetes is crucial for tailored treatment and management.

Type 1 Diabetes

Type 1 Diabetes is an autoimmune disease in which the body's immune system destroys the insulin-producing beta cells in the pancreas.

  • Key Features: Typically diagnosed in childhood or adolescence, requires lifelong insulin therapy, and is not preventable.
  • Cause: Autoimmune reaction, not linked to lifestyle factors.

Type 2 Diabetes

Type 2 Diabetes is a condition in which the body does not use insulin properly (insulin resistance) and the pancreas gradually loses its ability to produce enough insulin.

  • Key Features: Typically develops in adulthood, often associated with obesity and lifestyle factors, and can sometimes be managed with diet, exercise, and oral medications, but may also require insulin therapy.
  • Risk Factors: Obesity, physical inactivity, family history, and older age.

Conclusion: Empowering Knowledge for Effective Diabetes Management

This glossary aims to provide a foundational understanding of the key terms and concepts involved in diabetes management. By familiarizing yourself with these terms, you’ll be better equipped to communicate with healthcare providers, make informed decisions about your health, and navigate the complexities of living with diabetes. Continuous learning and staying informed are essential for effective diabetes management and overall well-being. Remember to consult your healthcare team for personalized advice and treatment plans tailored to your specific needs.

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