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Emergency Steps to Take for Severe Hypoglycemia (Low Blood Sugar)
17 Sep 2025 By Sagar Dugani, M.D., Ph.D.

Emergency Steps to Take for Severe Hypoglycemia (Low Blood Sugar)

Severe hypoglycemia, or dangerously low blood sugar, is a critical medical condition that can arise in individuals with diabetes, particularly those who use insulin or certain oral medications. Recognizing and responding swiftly to severe hypoglycemia can prevent serious complications, including seizures, loss of consciousness, brain damage, and even death. This article outlines the emergency steps you need to take when someone experiences severe hypoglycemia, providing clear, actionable guidance for immediate response.

What is Severe Hypoglycemia?

Hypoglycemia occurs when blood glucose levels drop too low—typically below 70 mg/dL (3.9 mmol/L). Severe hypoglycemia is defined as a state of very low blood sugar that requires assistance from another person to treat. It is characterized by symptoms such as confusion, disorientation, seizures, or unconsciousness.

Why is it Important to Act Quickly?

The brain relies on glucose for energy. When blood sugar levels plummet, the brain's function is impaired, leading to neurological symptoms. Prolonged or severe hypoglycemia can result in irreversible brain damage. Rapid intervention is crucial to restore blood glucose levels and prevent these complications. How Persons With Diabetes Can Prevent Severe Hypoglycemia

Recognizing the Signs and Symptoms

Being able to recognize the symptoms of hypoglycemia is crucial for effective intervention. Symptoms can vary from person to person, and it’s essential to understand an individual’s typical pattern. Common signs and symptoms include: Hypoglycemia Vs Hyperglycemia Recognizing The Signs Of A Blood Sugar Imbalance

  • Mild to Moderate Hypoglycemia:
    • Shakiness
    • Sweating
    • Rapid heartbeat
    • Anxiety
    • Irritability or confusion
    • Dizziness
    • Hunger
    • Blurred vision
    • Weakness
  • Severe Hypoglycemia:
    • Inability to eat or drink
    • Seizures
    • Loss of consciousness

It's important to note that some people may not experience any warning signs (hypoglycemia unawareness), which can increase the risk of severe episodes. Regular monitoring of blood glucose levels is particularly important in such cases.

Immediate Actions for Severe Hypoglycemia

When someone is experiencing severe hypoglycemia, follow these steps:

1. Assess the Situation

First, determine if the person is conscious and able to swallow. Do not attempt to give anything by mouth to an unconscious person, as this could cause choking. Look for medical identification, such as a medical alert bracelet or necklace, which may indicate that the person has diabetes.

2. Administer Glucagon (If Available)

Glucagon is a hormone that raises blood sugar levels. If the person is unable to take oral glucose and you have a glucagon emergency kit, administer the glucagon immediately.

  • How to Administer Glucagon:

    1. Check the expiration date on the glucagon kit.
    2. Prepare the glucagon: Typically, this involves mixing a powdered form of glucagon with a liquid diluent. Follow the instructions in the kit carefully.
    3. Administer the injection: Inject the glucagon into the thigh, arm, or buttock. It can be injected through clothing if necessary.
    4. Note the time of injection: This information is important for medical personnel.
    5. What to Expect After Glucagon Administration:

    6. It may take 10-15 minutes for the person to regain consciousness.

    7. Once the person is awake and able to swallow, give them a fast-acting source of glucose (see step 4).
    8. Glucagon can sometimes cause nausea or vomiting. Turn the person on their side to prevent choking if vomiting occurs.

3. If Glucagon is Not Available, Call for Emergency Medical Assistance

If you do not have glucagon or are not comfortable administering it, call emergency services (911 in the United States, 112 in Europe, or your local emergency number) immediately. Provide them with the following information:

  • That the person is unconscious or having a seizure.
  • That you suspect severe hypoglycemia.
  • Any relevant medical history, if known (e.g., the person has diabetes).
  • Your location.

Stay with the person until emergency responders arrive.

4. Once Conscious, Provide Fast-Acting Glucose

Once the person regains consciousness and is able to swallow, give them a fast-acting source of glucose to quickly raise their blood sugar. Examples include:

  • Glucose tablets or gel: Follow the product instructions for dosage.
  • Fruit juice: About 4 ounces (120 ml).
  • Regular (non-diet) soda: About 4 ounces (120 ml).
  • Hard candies: About 3-4 pieces.
  • Honey or corn syrup: About 1 tablespoon.

Avoid foods high in fat, such as chocolate, as they can slow the absorption of glucose.

5. Monitor Blood Sugar Levels

After providing fast-acting glucose, monitor the person's blood sugar levels every 15 minutes. If blood sugar remains low (below 70 mg/dL or 3.9 mmol/L), repeat the fast-acting glucose treatment.

6. Provide a Longer-Acting Carbohydrate Source

Once the blood sugar is above 70 mg/dL and the person is feeling better, give them a longer-acting carbohydrate source to help stabilize their blood sugar and prevent another drop. Examples include:

  • Crackers with peanut butter or cheese
  • A sandwich
  • A piece of fruit

7. Seek Medical Evaluation

Even if the person recovers fully, it's essential to seek medical evaluation. Severe hypoglycemia can be a sign of underlying issues with diabetes management, and a healthcare professional can assess the situation and make necessary adjustments to the person’s treatment plan.

Preventing Future Episodes of Severe Hypoglycemia

Prevention is key to reducing the risk of severe hypoglycemia. Here are some strategies:

  • Regular Blood Glucose Monitoring: Frequent monitoring helps identify trends and potential risks.
  • Consistent Meal Timing: Eating meals and snacks at regular intervals helps maintain stable blood sugar levels.
  • Medication Management: Understanding the effects and timing of insulin and other diabetes medications is crucial. Adjusting doses based on activity levels, meals, and blood sugar readings is often necessary.
  • Educating Family and Friends: Make sure family members, friends, and coworkers know how to recognize and treat hypoglycemia. Teach them how to administer glucagon.
  • Wearing Medical Identification: A medical alert bracelet or necklace can provide vital information to first responders in an emergency.
  • Continuous Glucose Monitoring (CGM): CGMs provide real-time glucose readings and can alert users to trends and potential low blood sugar levels.
  • Working with a Healthcare Team: Regular check-ups with a diabetes educator, endocrinologist, and other healthcare professionals can help optimize diabetes management.

Specific Scenarios and Considerations

Hypoglycemia Unawareness

Some individuals with diabetes may develop hypoglycemia unawareness, where they no longer experience the typical warning signs of low blood sugar. In these cases, frequent blood glucose monitoring and the use of a CGM are particularly important. Consider setting target blood sugar levels higher to avoid lows, and work closely with a healthcare provider to manage this condition.

Nighttime Hypoglycemia

Nighttime hypoglycemia can be particularly dangerous as it can go unnoticed. Symptoms might include nightmares, sweating, or waking up with a headache. To prevent nighttime lows:

  • Check blood sugar levels before bed.
  • Have a bedtime snack that includes complex carbohydrates and protein.
  • Consider using a CGM with alarms for low blood sugar.
  • Adjust insulin doses or timing as recommended by a healthcare provider.

Hypoglycemia and Exercise

Physical activity can significantly lower blood sugar levels. To prevent hypoglycemia during or after exercise: What Is A Dangerous Level Of Low Blood Sugar Hypoglycemia

  • Check blood sugar levels before, during, and after exercise.
  • Have a carbohydrate snack readily available.
  • Adjust insulin doses or carbohydrate intake based on the intensity and duration of exercise, as advised by a healthcare professional.

Tools and Resources

  • Glucagon Emergency Kit: Ensure you have an up-to-date kit and that family members know how to use it.
  • Continuous Glucose Monitors (CGM): These devices provide real-time glucose readings and can alert you to potential lows.
  • Blood Glucose Meters: Regular monitoring is crucial, especially for those at risk of hypoglycemia.
  • Diabetes Education Programs: Certified Diabetes Educators can provide comprehensive education and support for managing diabetes.
  • Medical Identification: A medical alert bracelet or necklace can provide vital information in an emergency.

Conclusion

Severe hypoglycemia is a serious medical emergency that requires prompt and effective action. Knowing how to recognize the symptoms, administer glucagon, provide fast-acting glucose, and prevent future episodes can save lives. By taking the necessary steps and working closely with a healthcare team, individuals with diabetes can minimize their risk and live healthy, active lives. Always seek professional medical advice for managing diabetes and addressing specific health concerns.

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