HbA1c vs Glucose: What’s The Difference?

Understanding the difference between HbA1c and glucose is crucial for anyone managing diabetes or at risk of developing it. These two measurements provide distinct insights into blood sugar levels, offering different perspectives on how well glucose is being controlled in the body. While both are related to blood sugar, they don't tell the same story. This article will explain what each measurement signifies, how they are obtained, and what each one reveals about your health.

Glucose, also known as blood sugar, is a simple sugar that serves as the body's primary source of energy. It circulates in the bloodstream and is used by cells for various functions. When you eat, your body breaks down carbohydrates into glucose, which then enters your bloodstream. The levels of glucose in your blood rise and fall throughout the day based on what you eat, your activity levels, and how your body regulates it with insulin. A finger-prick test or a venous blood draw are the methods to directly check this level at any given time. However, measuring it just once offers just a snapshot in time. It can change quickly, giving limited insight about long-term diabetes control.

HbA1c, or glycated hemoglobin, on the other hand, provides a long-term picture of average blood sugar levels. This test measures the percentage of red blood cells that have glucose attached to them. Because red blood cells typically live for about three months, HbA1c gives a picture of blood sugar control over the past 2-3 months. It offers a much broader view than any single glucose measurement. For example, an individual may show normal glucose on a given day, but if their blood sugar has been consistently high over the past few months, their HbA1c will still show this.

Aspect	Glucose	HbA1c
What it measures	Instant blood sugar level	Average blood sugar over 2-3 months
Time Frame	Present Moment	Past 2-3 months
Test Type	Blood Test	Blood Test
Frequency	As needed	Typically every 3-6 months
Insight Provides	Current glucose levels	Long-term blood sugar control
Variability	Highly variable	More stable

---

Decoding Glucose Levels: A Real-time Snapshot

Glucose levels are dynamic, constantly shifting in response to meals, activity, stress, and medications. This variability is why glucose monitoring, either through a finger-prick test or a continuous glucose monitor (CGM), is essential for many individuals, especially those managing diabetes. Here is what blood glucose levels indicate:

• Fasting Blood Glucose: Typically measured after an overnight fast (8 hours). A normal fasting glucose blood sugar level 258 range is generally between 70 and 100 mg/dL (3.9 to 5.6 mmol/L).
• Postprandial (After-Meal) Glucose: Measured about 2 hours after a meal. Levels will naturally rise after eating. For non-diabetic people, this number generally returns to normal range within a few hours. It should ideally be below 140 mg/dL (7.8 mmol/L) after 2 hours.

The values that fall out of these ranges usually warrant more attention and can indicate the following:

• High Glucose (Hyperglycemia): This indicates an excess of sugar in the blood, a symptom of untreated or poorly managed diabetes. Consistent high glucose levels can lead to a number of complications over time.
• Low Glucose (Hypoglycemia): A significant drop in blood sugar levels can happen suddenly and requires immediate action to raise glucose.

Regular glucose monitoring provides instant feedback which is vital for daily diabetes management. If you see that you're having high glucose numbers more often than you should be or low glucose events occur frequently, these observations are critical for adjusting medications or making meal changes on a day-to-day basis. It should be noted, that glucose levels change for everyone, and may fluctuate quite significantly in people with diabetes.

Glucose Level	General Guideline	Potential Implications
Fasting: Below 70 mg/dL (3.9 mmol/L)	Low	Hypoglycemia, needs prompt attention
Fasting: 70-100 mg/dL (3.9-5.6 mmol/L)	Normal (General Target)	Usually a healthy blood sugar level
Fasting: 100-125 mg/dL (5.6-6.9 mmol/L)	Pre-diabetes (Impaired Fasting Glucose)	Increased risk of developing diabetes
Fasting: 126 mg/dL or higher (7.0 mmol/L or higher)	Diabetes	Requires further investigation will nuts raise blood sugar and management
2-Hours Post Meal: Below 140 mg/dL (7.8 mmol/L)	Normal	Generally a healthy blood sugar level
2-Hours Post Meal: 140-199 mg/dL (7.8-11.0 mmol/L)	Prediabetes (Impaired Glucose Tolerance)	Increased risk of developing diabetes
2-Hours Post Meal: 200 mg/dL or higher (11.1 mmol/L or higher)	Diabetes	Requires further investigation and management

---

Understanding HbA1c: The Long-Term Indicator

While daily glucose monitoring is critical, it only reveals your blood sugar at a given moment. HbA1c, however, offers a more stable, comprehensive look at your glucose levels over a longer period, and helps your medical care team understand how effective your treatment regimen has been, or if there needs to be changes made to better regulate blood sugars.

The HbA1c test measures how much glucose has attached to hemoglobin. Hemoglobin is the oxygen-carrying normal blood sugar for hypoglycemia protein in your red blood cells. The higher your average blood glucose levels over the preceding 2-3 months, the more glucose gets attached to these proteins, resulting in a higher HbA1c result. Here's how the ranges are generally interpreted:

• Normal HbA1c: Less than 5.7%. This suggests that your average blood sugar levels are within a healthy range.
• Pre-diabetes HbA1c: Between 5.7% and 6.4%. This indicates that your blood sugar levels are higher than normal but not yet in the diabetes range. People with pre-diabetes are at higher risk of developing type 2 diabetes in the future.
• Diabetes HbA1c: 6.5% or higher. This confirms a diagnosis of diabetes and suggests long-term high blood glucose levels.

HbA1c levels are used not only for diagnosing diabetes but also for monitoring the effectiveness of diabetes treatments. If someone's HbA1c level is consistently high (above target), adjustments might need to be made to their treatment plan, which could include changes to medication, diet, or exercise. It should also be stated that an HbA1c target goal is usually set on an individual basis, often times between 6.5-7%, however, this number is based on multiple factors including duration of disease, health history, age, etc. This number may also fluctuate depending on individual's specific health situations.

HbA1c Level	Interpretation	General Medical Implications
< 5.7%	Normal	Healthy blood sugar control
5.7% - 6.4%	Pre-diabetes	Increased risk of developing diabetes
≥ 6.5%	Diabetes	Confirms diabetes; needs active management

---

Integrating Glucose Monitoring and HbA1c in Diabetes Management

Both glucose monitoring and HbA1c measurements provide unique, vital information for effectively managing diabetes. They are not interchangeable but complement each other, providing a comprehensive understanding of blood sugar levels:

• For Daily Management: Regular glucose monitoring, whether with a finger-stick test or continuous glucose monitor (CGM), helps individuals make informed decisions about diet, exercise, and medication on a daily basis. It allows them to identify patterns, make immediate adjustments to avoid low or high blood sugar levels, and stay within their target range.
• For Long-Term Insight: HbA1c offers insight into the effectiveness low blood sugar cause nausea of overall blood sugar management. This data is usually interpreted by the healthcare team to determine what is working, what is not, and where changes need to be implemented. It also provides a way to evaluate long-term glycemic control, which helps lower the risks of diabetes-related complications.

Function	Glucose Monitoring	HbA1c Measurement
Frequency	As needed (multiple times a day for some)	Typically every 3-6 months
Primary Goal	Immediate Control	Long-term blood sugar control
Insights for daily management	Patterns in blood sugar variations due to lifestyle	Overall treatment effectiveness
Help for Adjustments	Allows short term changes	Guides long-term management decisions

In essence, glucose monitoring is your immediate compass, guiding your day-to-day decisions and keeping you in a healthy range. HbA1c is your long-term blood sugar chart download road map, guiding overall treatment strategies. Both are essential for maintaining optimal health and effectively managing diabetes, giving both patient and healthcare team members a powerful tool in effective disease management.

Understanding the difference between HbA1c and glucose helps people with diabetes make better choices that ultimately support long-term health and wellbeing. By using both measures, a more complete and actionable approach to diabetes can be achieved.

The right sweet foods can help you lose weight and keep it off! Here's how to do it. ♥️ 👀 Next: Fight Fatty Liver & Diabetes: Top 10 Foods To Eat ♥️ Check Out My Favorite Daily Immunity Supplement: NACPRO+ Shape Our Content: Tell Us What You Want! Welcome to @HealthyImmuneDoc ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ The trauma of working in the frontlines as an acute and critical care Infectious Disease specialist during the chaos and stress of 2020-21, motivated Dr. Liu to promote practical health and wellness principles for her community. HealthyImmuneDoc youtube channel is an extension of her education campaign to help people understand how to optimize immunity and inflammation and slow down premature aging caused by acute and chronic conditions. Everyone is welcome! Dr. Liu’s Bio ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Dr. Liu is the co-founder of NACPro+, dedicated to optimizing immunity and wellness. Dr. Liu graduated from Loma Linda University School of Medicine in 1998 and is Double Boarded in Infectious Disease and Internal Medicine. She is licensed in the state of California. This channel is separate from Dr. Liu’s duties as Attending Medical Staff @ Cedars-Sinai Medical Center and as Assistant Professor at Loma Linda University School of Medicine. The views on this channel are her own. VIDEO TOPICS: ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ 00:00 Introduction 00:28 Bliss Point 01:20 Mood & Sugar 02:29 Peanut Butter Dates 03:01 Khadrawy Date 03:18 Negative Loops & Cravings 03:51 Fat & Sugar 04:23 Insulin Resistance 05:51 Fiber 06:04 Refined Sugar 07:24 Dates 07:50 Potassium 08:10 Sodium:Potassium Ratio 09:01 Peanut Cookie 09:37 Obesogens 10:10 Mango 10:37 Vitamin C 12:10 Sugar Spikes 13:58 Nutrient Dense Foods 14:16 Glucose & Glycation 14:45 Advance Glycation End Products 15:53 Hemoglobin a1c 16:25 Cavities & Acid 16:54 Petri Dish 17:20 Sapote 19:26 Glucose versus Fructose 19:58 Fatty Liver 20:25 Alcohol 21:24 Stomach Cancer 21:40 Auto Brewey Syndrome 23:40 Coffee Polyphenols & Dairy 23:52 Creamer 25:20 High Protein Pudding 26:30 Sweet Bean Soups 26:52 Jujube Dates 27:22 Sweet Tea 29:02 Chocolate Mousse 29:47 Sugar Cane LEGAL DISCLAIMERS: ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ Sorry, occupational hazard: This is NOT medical advice, nor can I give you medical advice. I AM NOT YOUR DOCTOR. This video does not create a doctor-patient relationship between Dr. Liu and you. Everything here is for general informational purposes only and not for the purpose of providing medical advice. Information in this video is not intended to be a substitute for professional medical advice and it should not be used to self-diagnose nor should it substitute for a medical exam, treatment, diagnosis, and prescription or other recommendations by a professional medical doctor. You should not make any changes in your health regimen or diet before first consulting a physician. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Users should not disregard or delay in obtaining medical advice from health care professionals for any medical condition. Also, some of the links in this post may be affiliate links, meaning, at no cost to you, I will earn a small commission if you click through and make a purchase. But if you click, it really helps me make more of these videos! All non-licensed clips are used for fair use commentary, criticism, and educational purposes. See Hosseinzadeh v. Klein, 276 F.Supp.3d 34 (S.D.N.Y. 2017); Equals Three, LLC v. Jukin Media, Inc., 139 F. Supp. 3d 1094 (C.D. Cal. 2015).